Research Technician - Littman Lab
Company: Howard Hughes Medical Institute (HHMI)
Location: New York
Posted on: April 16, 2024
Job Description:
Primary Work Address: NYU Medical Center, New York, NY,
10016-6481Current HHMI Employees, click here to apply via your
Workday account.The Littman laboratory at New York University is
seeking a dynamic, driven, and curious Research Technician to join
our group. The Littman lab investigates how T lymphocytes acquire
functional properties during development and in response to
distinct intestinal microbiota that influence systemic inflammatory
processes (e.g. T cell-mediated autoimmune diseases, immune control
of tumor growth, and responses to infection with pathogenic
microbes). We also study how the immune system and the microbiota
interact with the enteric and central nervous systems at
homeostasis and under pathological conditions. More information on
the lab can be found on our website: We are looking for a highly
motivated individual who is passionate about science and wishes to
contribute to furthering our understanding in these newly emerging
areas. This individual will be an integral member of the lab,
working with a dynamic and diverse group of scientists in the areas
of immunology, microbiome, neuroimmunology, single cell genomics,
transcriptional regulation, and mouse genetics. This position will
involve providing experimental support for one or more postdoctoral
fellows, and the candidate will need to be comfortable managing
multiple priorities and their time. Ideal candidates will be
determined, creative, and willing to tackle novel challenges, and
will have the opportunity to develop an independent project.This is
an ideal opportunity for a recent college graduate who would like
to gain more hands-on research experience in an academic laboratory
environment before attending graduate school in the biological
sciences. We are targeting candidates looking to stay within the
lab for 2-3 years before moving on. Several of our previous
technicians have made important contributions to research projects
resulting in co-authorship on scientific publications.To apply, in
addition to your resume, please include: a 1-page cover letter
including the following information: - Why are you interested in
this position? -What do you want to learn from this job? - Why do
you think you would be a good fit for the position? - What are
potential start dates that would work for you? - What are your long
and short-term career goals (including your ideal time frame for
the next stages in your career)?What we provide:
- A competitive compensation package with comprehensive health
and welfare benefits.
- An opportunity to broaden research experience in a
collaborative environment.
- One-on-one mentorship relationships.
- Professional and educational development opportunities.
- A vibrant and inclusive lab and research community.What you'll
do:
- Cooperate with lab members in performing experiments in
molecular biology, immunology, immune-nervous system interactions,
and the microbiome.
- Help with maintenance and organization of lab mouse strains,
including DNA extraction and PCR from isolated mouse tissue for
genotyping.
- Perform a variety of laboratory and investigative procedures
with mouse models, including colonizing mice with defined
microbiota, performing cell transfers into mice, harvesting and
processing of mouse tissues for flow cytometry, genomics, and
imaging studies.
- Culture and maintain mammalian cell culture lines, and use
standard molecular biology techniques, including CRISPR technology,
to modify genes in primary immune system cells.
- Collect, verify, record and compile data and information,
keeping a detailed electronic notebook.
- Assist with experimental design and establishing new protocols
and maintaining lab equipment.
- Instruct others in basic laboratory techniques.
- Help with lab organization and other support duties relating to
lab operations as required, while looking for ways to improve lab
processes.
- Participate in laboratory meetings and read literature
applicable to the research area.
- The successful candidate will perform tasks related to the
research project independently while under the guidance and
mentorship of the supervisor.What you bring:
- Bachelor's degree in life science, preferably with courses in
molecular and cell biology and immunology or neuroscience.
- Background training and knowledge of molecular and cell
biology
- Prior experience working in a hands-on research lab for at
least one year.
- Prior mouse handling experience a plus (breeding, weaning and
maintaining lines, tail DNA prep).
- Tissue culture of mammalian cells and molecular cloning skills
preferred.
- Knowledge of basic laboratory practices and techniques.
- Strong interpersonal skills, in addition to the ability to work
both independently and as part of an interdisciplinary team.
- Excellent analytical, communication, and computer skills, with
attention to detail.
- Strong self-motivation with excellent time management and
organizational skills.
- Passion for science and continuous education, actively seeking
opportunities to increase skills and expertise.
- Ability to learn complex tasks with instruction, and to use
experience to perform a variety of new techniques.Physical
RequirementsRemaining in a normal seated or standing position for
extended periods of time; reaching and grasping by extending
hand(s) or arm(s); dexterity to manipulate objects with fingers,
for example using a keyboard; communication skills using the spoken
word; ability to see and hear within normal parameters; ability to
move about workspace. The position requires mobility, including the
ability to move materials weighing up to several pounds (such as a
laptop computer or tablet). Work may involve possible exposure to
malodorous vapors, low dose radiation, contamination by toxic
chemicals and acids and presence of carcinogenic substances.Persons
with disabilities may be able to perform the essential duties of
this position with reasonable accommodation. Requests for
reasonable accommodation will be evaluated on an individual
basis.Please Note:This job description sets forth the job's
principal duties, responsibilities, and requirements; it should not
be construed as an exhaustive statement, however. Unless they begin
with the word "may," the Essential Duties and Responsibilities
described above are "essential functions" of the job, as defined by
the Americans with Disabilities Act.Compensation and Benefits Our
employees are compensated from a total rewards perspective in many
ways for their contributions to our mission, including competitive
pay, exceptional health benefits, retirement plans, time off, and a
range of recognition and wellness programs. Visit our Benefits at
HHMI site to learn more.Compensation Range$18.52 (minimum) - $23.17
(midpoint) - $30.08 (maximum)Pay Type:HourlyHHMI's salary structure
is developed based on relevant job market data. HHMI considers a
candidate's education, previous experiences, knowledge, skills and
abilities, as well as internal equity when making job offers.
Typically, a new hire for this position in this location is
compensated between the minimum and the midpoint of the salary
range.HHMI is an Equal Opportunity Employer
Keywords: Howard Hughes Medical Institute (HHMI), Newark , Research Technician - Littman Lab, Healthcare , New York, New Jersey
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